Natural Progesterone Cream > Natural Progesterone Cream Benefits According to the research or Dr. John Lee and other physicians, natural progesterone cream is one way to help women overcome symptoms associated with peri-menopause and menopause. Dr. Lee found that synthetic progesterones used in many pills and tablets were not as effective as natural progesterone cream and suggested a natural progesterone cream that by-passes the human liver's very effective filtering ability so all the beneficial attributes of progesterone could spread throughout a woman's body to provide relief. Natural progesterone cream goes beyond synthetic progesterone to give relief from the symptoms that can often accompany peri-menopause and menopause.