Natural Progesterone Cream Progesterone Cream made from natural progesterone is the product of anthropological observation and medical research. In the 1930s anthropologists discovered that certain women's illnesses such as PMS and breast cancer were virtually unknown in the Trobriand Islands, a remote chain in the South Pacific. Their health secret was the high concentration of wild yam that made up about three-quarters of the local diet. This particular food family which includes Mexican wild yam contains significant concentrations of diosgenin, one of the finest sources of natural progesterone. Medical researchers such as Dr. John Lee have found that topical, transdermal progesterone cream relieves pre-menopause, peri-menopause and menopause symptoms better than synthetic, bioengineered substances. His research showed that while progesterone pills and tablets are mostly lost through the liver before their chemicals entered the blood stream, a mild natural skin cream provided a safe, pleasant and efficient way to help a woman's body help itself. Natural human progesterone is produced by a piece of egg follicle, the corpus luteum, left behind in the ovaries after ovulation when the egg is released toward the uterus and later from the placenta during pregnancy. During peri-menopause, when natural human progesterone diminishes, the excess of estrogen leads to a condition called estrogen dominance by Dr. John Lee. Rather than using pills or tablets, Dr. Lee recommends a topical, transdermal cream with natural progesterone from wild yam that enters the system without interference from the liver. The progesterone is made up of small, fat soluble molecules that are absorbed by the fat layers under the skin and diffused throughout the body via the bloodstream. During peri-menopause and menopause the natural progesterone cream helps fight osteoporosis, endometriosis, fibroid tumors, and breast cancer. It gives relief from hot flashes, restores female libido, vaginal dryness and other menopause symptoms.