Natural Progesterone Cream > Progesterone Progesterone has often been called "the forgotten hormone" because its primary function is to help the body produce and regulate certain other steroid hormones. The production of progesterone, which, along with estrogen, is one of a woman's two most important hormones, either stops completely with the end of ovulation or is produced irregularly. Estrogen continues to build up, especially in a woman's uterine lining causing the symptoms of pre-menopause and peri-menopause. Other symptoms of what is known as estrogen dominance include hot flashes, vaginal dryness and mood changes. These symptoms are mild for some women, but they can be so severe for others as to make their lives unbearable. Breakthrough research, especially by Dr. John Lee, has demonstrated that for many women natural progesterone cream is a viable treatment that can reduce menopause symptoms by permeating the skin and entering the blood stream from which it is released throughout the body to raise the depleted hormonal level.